• Anaesthesia · Sep 1987

    Suxamethonium in myasthenia gravis.

    • A P Wainwright and P M Brodrick.
    • National Hospital for Nervous Diseases, Queen Square, London.
    • Anaesthesia. 1987 Sep 1; 42 (9): 950-7.

    AbstractThe effects of suxamethonium 1.0 and 0.5 mg/kg were studied in myasthenic patients. Resistance was not encountered at the 1.0 mg/kg dose but was seen at the lower dose. A non-depolarising type of block developed in patients in both groups. However, recovery from the non-depolarising block was not prolonged beyond the requirements of surgery. The neurophysiological basis for, and clinical implications of these findings are discussed.

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