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Turk J Gastroenterol · Aug 2011
Case ReportsSevere jaundice due to coexistence of Dubin-Johnson syndrome and hereditary spherocytosis: a case report.
- Uğur Korkmaz, Ali Erkan Duman, Deniz Oğütmen Koç, Yeşim Gürbüz, Gökhan Dındar, Fatih Ensaroğlu, Selçuk Yusuf Sener, Omer Sentürk, and Sadettin Hülagü.
- Kocaeli University Medical Faculty, Department of Gastroenterology, Kocaeli, Turkey. drkorkmazugur@yahoo.com
- Turk J Gastroenterol. 2011 Aug 1; 22 (4): 422-5.
AbstractDubin-Johnson syndrome is a chronic, benign, intermittent jaundice, mostly of conjugated hyperbilirubinemia. The level of bilirubin is not expected to be more than 20 mg/dl in this syndrome. In this article, we report a patient who was evaluated for hyperbilirubinemia and liver function test abnormalities and diagnosed with Dubin-Johnson syndrome coexisting with hereditary spherocytosis. We suggest that other diseases should be investigated if patients with Dubin-Johnson syndrome present with severe hyperbilirubinemia. Dubin-Johnson syndrome accompanied by hemolytic diseases might also have high coproporphyrin levels (as in Rotor's syndrome) than expected in pure Dubin-Johnson syndrome.
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