• Seok Joon Yoon, Sang-Yeon Suh, Yong Joo Lee, Jeanno Park, Sunwook Hwang, Sanghee Shiny Lee, Hong Yup Ahn, Su-Jin Koh, and Keon Uk Park.
• 1 Department of Family Medicine, Chungnam National University Hospital , Daejeon, South Korea .
• J Palliat Med. 2017 Jan 1; 20 (1): 65-68.

BackgroundObjective Prognostic Score (OPS) was developed as an easy and simple prognosticating tool in South Korea. It has been validated retrospectively in a single center in South Korea.ObjectiveWe aimed to validate the OPS prospectively for advanced cancer inpatients in South Korea using a multicenter study.DesignThis was a prospective cohort study.Setting/SubjectsWe enrolled 243 advanced cancer patients admitted in five palliative care units in South Korea from May 2013 till March 2015. Seven members of the Korean Palliative Medicine Research Network who are experts of palliative care led the study.MeasurementsClinical variables (dyspnea/anorexia/performance status) and laboratory variables (total leukocyte counts/serum total bilirubin/serum creatinine/lactate dehydrogenase) were collected at the enrollment. Survival time was calculated as days from enrollment to death during admission.ResultsA total of 217 patients were included in the final analysis (feasibility: 89.3%). Survival time of the higher OPS group (OPS ≥3) and the lower OPS group (OPS <3) was 10.0 (95% confidence interval (CI) 7.72-12.28) days and 32.0 (95% CI 25.44-38.56) days, respectively. There were significant differences between the 2 groups (p < 0.001). Overall accuracy of OPS ≥3 for predicting survival less than three weeks was 71.0%.ConclusionsOPS was successfully validated using a prospective multicenter study in South Korea. It is a useful method to predict three-week survival of Korean inpatients with advanced cancer.

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