• Am J Emerg Med · May 2017

    Case Reports

    Numb chin syndrome: A harbinger of tumor progression or relapse.

    • Namasivayam Balamurugan, S V Arathisenthil, Subramanian Senthilkumaran, and Ponniah Thirumalaikolundusubramanian.
    • Department of Neurosciences, SIMS Chellum hospital, Salem, Tamil Nadu, India.
    • Am J Emerg Med. 2017 May 1; 35 (5): 805.e1-805.e2.

    AbstractNumb chin syndrome (NCS) is a rare yet potentially ominous sensory neuropathy in the distribution of the mental or inferior alveolar nerve characterized by unilateral hypoesthesia over the lower lip, chin and occasionally gingival mucosa. Recognizing NCS is clinically important as this may be a subtle sign of occult malignancy progression or heralding the relapses. It may also occur in benign disease, both systemic and dental in origin. Current expert opinion is that patients with NCS without apparent cause should be assumed to have a malignant etiology until proven otherwise Lossos and Siegal (1992) [1]. Here we report a relapse of Non-Hodgkin lymphoma with NCS with no evidence of metastasis.Copyright © 2016 Elsevier Inc. All rights reserved.

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