• World Neurosurg · Aug 2017

    Review Meta Analysis Comparative Study

    Clipping versus coiling, in anterior circulation ruptured intracranial aneurysms: A meta-analysis.

    • George Fotakopoulos, Eleni Tsianaka, Kostas Fountas, Demosthenes Makris, Michael Spyrou, and Juha Hernesniemi.
    • Department of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Larissa, Thessaly, Greece. Electronic address: gfotakop@yahoo.gr.
    • World Neurosurg. 2017 Aug 1; 104: 482-488.

    ObjectiveTo evaluate open surgical versus endovascular repair of anterior circulation ruptured intracranial aneurysms based on operative mortality, permanent neurologic deficit, late mortality, and need for reintervention.MethodsThis meta-analysis included articles published since December 6, 2016, that compared outcomes of the 2 methods. Extracted data were organized in a standard table format, including first author, country, covered study period, publication year, number of patients and patients at follow-up, operative mortality rate (with 30 days from treatment), permanent neurologic deficit (appearing after surgery), late mortality (after 1 month), and reintervention (surgery or coiling) for both groups of patients. Follow-up was at least 1 year.ResultsThere were 8 articles that matched our study criteria. The study population was 628 patients; 374 were treated with surgical clipping, and 254 were treated with endovascular coiling. Pooled results showed no statistically significant difference between the 2 groups in terms of operative mortality, permanent neurologic deficit, late mortality, and need for reintervention.ConclusionsSelection of the appropriate procedure must be made on the basis of the special characteristics of each case.Copyright © 2017 Elsevier Inc. All rights reserved.

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