• World Neurosurg · Dec 2018

    Review Case Reports

    Multiple Cavernous Malformations of Brain, Chest, and Skin: A Rare Case of an Infant and Literature Review.

    • Xinke Xu, Junliang Li, Cheng Chen, Fenghua Wang, and Fangcheng Li.
    • Department of Neurosurgery, Guangzhou Women and Children's Medical Center, Guangzhou, China.
    • World Neurosurg. 2018 Dec 1; 120: 177-180.

    BackgroundCerebral cavernous malformations (CCMs) are vascular malformations that account for 5%-15% of all central nervous system vascular malformations. However, multiple CCMs, which can be sporadic or familial, are rare, with a prevalence of 0.1%-0.5%.Case DescriptionHere, we presented a rare case of sporadic multiple CCMs in an infant, which were accompanied with multiple cavernous malformations of the chest and skin.ConclusionsCCMs were pathologically diagnosed through the total resection of the pineal regional lesion. We also observed a spontaneous regression of the remaining lesions during a follow-up period of 2 years. To our knowledge, this is the first case of CCMs in an infant in the English-language literature.Copyright © 2018 Guangzhou Women and Children's Medical Center. Published by Elsevier Inc. All rights reserved.

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