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  • Acta Anaesthesiol Scand · Sep 2012

    Case Reports

    Intravenous fluorescein as a cause of immunoglobulin E-mediated anaphylactic shock.

    • A Breidablik, G H De Pater, C Walther, A Nopp, and A B Guttormsen.
    • Department of Anaesthesiology and Intensive Care, Central Hospital of Sogn og Fjordane, Førde, Norway.
    • Acta Anaesthesiol Scand. 2012 Sep 1;56(8):1066-8.

    AbstractWe report a patient with severe anaphylactic shock immediately after injection of i.v. fluorescein. The patient recovered without sequela. Immunoglobulin E (IgE) mechanism was highly suggestive with significant increase in serum tryptase, positive basophil allergen threshold sensitivity (CD-sens) and histamine release tests towards fluorescein. This is, to our knowledge, the first report where CD-sens has been used to aid in diagnosing an IgE-mediated anaphylactic shock caused by fluorescein.© 2012 The Authors. Acta Anaesthesiologica Scandinavica © 2012 The Acta Anaesthesiologica Scandinavica Foundation.

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