• Ondrej Jor, Jan Maca, Jirina Koutna, Michaela Gemrotova, Tomas Vymazal, Martina Litschmannova, Pavel Sevcik, Petr Reimer, Vera Mikulova, Michaela Trlicova, and Vladimir Cerny.
• Department of Anesthesiology and Intensive Care Medicine, University Hospital Ostrava, 17. listopadu 1790, Poruba, 708 52, Ostrava, Czech Republic. ondra_jor@centrum.cz.
• J Anesth. 2018 Oct 1; 32 (5): 673-680.

BackgroundHypotension after induction of general anesthesia (GAIH) is common in anesthesiology practice and can impact outcomes.MethodsIn this prospective multicenter, cross-sectional, observational study, the hypotension was defined as a decrease in mean arterial pressure of > 30% compared to the first measurement in the operation theatre before general anesthesia (GA) induction. Blood pressure was measured immediately at the time of endotracheal intubation (TETI), at five (T5) and 10 (T10) minutes after. All subjects aged > 18 years undergoing elective non-cardiac surgery under GA were included. The goals were description of GAIH occurrence, the association of GAIH with selected comorbidities, chronic medications, and anesthetics with GAIH, and the type and efficacy of interventions used to correct hypotension.ResultsData from 661 subjects, whose GA was induced with propofol and sufentanil, were analyzed. In 36.5% of subjects, GAIH was observed at ≥ 1 of the assessed time points. GAIH was present in 2.9% subjects at all time points. The probability of GAIH is raising with age, degree of hypertension at time of arrival to theatre and presence of diabetes. The type of volatile anesthetic was not associated with the occurrence of GAIH. The overall efficiency of interventions to correct hypotension was 94.4%. Bolus fluids were the most often used intervention and was 96.4% effective.ConclusionGAIH rate depends on age, degree of blood pressure decompensation prior the surgery, and presence of diabetes mellitus type II.

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