• Fan Chen, Bo Chen, Haifeng Wang, Weidong Xu, Weichen Li, and Dawei Chen.
• Department of Neurosurgery, First Hospital of Jilin University, Changchun, China.
• World Neurosurg. 2018 Dec 1; 120: 234-239.

BackgroundIntracranial nonskull-based chondrosarcoma is a very rare malignant tumor. In fact, it is difficult to diagnose because of its atypical radiologic and morphologic features. We report a case of an intracranial parasagittal chondrosarcoma in the left parietal lobe accompanied with significant peritumoral edema (an extremely rare phenomenon for this tumor), with a review of the literature, to clarify aspects in the diagnosis of this rare tumor.MethodsA literature search was using PubMed with specific key terms, inclusion criteria, and exclusion criteria. Selected case studies and case series were then compared and summarized them in Table 1. A 59-year-old male patient presented with a history of progressive right hemiparesis and loss of sensation for 45 days.ResultsMagnetic resonance imaging revealed a 2.6 × 2.4 × 2.8-cm mass arising from the superior sagittal sinus in his left parietal lobe. A left parietal parasagittal craniotomy was performed, and a macroscopically complete excision of the tumor was achieved. The patient recovered well postoperatively. Regular follow-up after 6 months revealed that he had almost recovered full strength to his right limbs, and there was no evidence of recurrence. Intracranial parasagittal chondrosarcoma in the parietal lobe is extremely rare.ConclusionsAlthough magnetic resonance imaging was performed, it is sometimes difficult to distinguish intracranial chondrosarcoma from meningioma and glioma, especially when the tumor arises from a nonskull base such as the meninges. Some cases could have significant peritumoral edema, although it is extremely rare. Histologic examination may aid in the diagnosis of this tumor. Neurosurgery is the most effective therapy for these tumors. Postoperative radiotherapy needs to be considered when the tumor is incompletely resected, has atypical histology, or is associated with significant peritumoral edema.Copyright © 2018 Elsevier Inc. All rights reserved.

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