• World Neurosurg · Dec 2018

    Utility of Early Post-operative MRI after Glioblastoma Resection: Implications on Patient Survival.

    • Oliver D Mrowczynski, Samer Zammar, Alexandre J Bourcier, Sara T Langan, Jason Liao, Charles S Specht, and Elias B Rizk.
    • Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA. Electronic address: omrowczynski@pennstatehealth.psu.edu.
    • World Neurosurg. 2018 Dec 1; 120: e1171-e1174.

    BackgroundThe standard of care for glioblastoma is surgical resection followed by combination temozolomide and radiation. Magnetic resonance imaging (MRI) is used preoperatively for tumor resection planning. In some instances, MRI is also obtained postoperatively to assess for any complications and to determine extent of resection. There is some question whether early routine postoperative imaging of patients after tumor resection is beneficial to long-term outcomes, especially with the increased scrutiny of increasing health care costs.MethodsIn this study we retrospectively analyze patients with glioblastoma treated at our institution, comparing the difference in overall survival and treatment regimens between patients who had early postoperative MRI versus patients who did not.ResultsWe determine that in our cohort of 125 patients, those with early postoperative MRI had no statistically significant overall survival difference compared with patients with no early postoperative MRI (P = 0.996). The median survival for the group with postoperative MRI was 378 days (95% confidence interval [CI], 242-443 days), and the median survival for the group without postoperative MRI was 308 days (95% CI, 203-445 days). Early postoperative MRI also did not significantly alter therapeutic regimens.ConclusionsAlthough early postoperative MRI may not significantly affect patient overall survival from a statistical standpoint or therapeutic regimens, this type of imaging may be important to hone resident and attending skill. We encourage other institutions to perform similar analyses to determine the overall survival benefit of early postoperative imaging after glioma resection for patients with glioblastoma.Copyright © 2018 Elsevier Inc. All rights reserved.

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