• Tianhao Wang, Zhihua Cai, Yongfei Zhao, Wei Wang, Guoquan Zheng, Zheng Wang, and Yan Wang.
• Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing, China; Department of Orthopaedics, General Hospital of Chinese People's Liberation Army, Beijing, China.
• World Neurosurg. 2019 Mar 1; 123: e294-e302.

ObjectiveTo develop finite element models of spine following osteotomy and evaluate the effect of number and location of cross-links (CLs) on long-segment instrumentation.MethodsA finite element model of instrumented spine following osteotomy was created from computed tomography images of a postoperative male patient with thoracolumbar kyphotic deformity. Five fixation models were established to simulate different number and location of CLs. Four loading conditions (flexion, extension, lateral bending, and axial rotation) were applied on the models. Range of motion (ROM), maximum value and distribution of stress on implants, and stress on vertebrae were compared between models.ResultsWith increased number of CLs, average ROM of instrumented segments was reduced by 2.37%, 1.89%, and 2.49% in flexion, extension, and lateral bending. ROM was reduced by 21.98% in loading axial rotation condition. With increased number of CLs, ROM tended to be limited. Peak stresses were located on rods during axial rotation, on proximal pedicle screws during flexion, and on the osteotomy site during extension and lateral bending. CLs had an effect of dispersing stress concentration.ConclusionsThe application of CLs enhanced the rigidity of the construct. With increased number of CLs, ROM of the construct was decreased, especially in axial rotation. CLs can also disperse the stress concentration. After comparing various CL configurations in different motion conditions, we believe that the optimal method is to place 2 CLs at the osteotomy site and the proximal segment.Copyright © 2018 Elsevier Inc. All rights reserved.

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