• World Neurosurg · May 2019

    Review Case Reports

    A Case of Primary Sellar Paraganglioma: Immunohistochemistry Resource and Review.

    • Seán B Lyne, Sean P Polster, Shiraz Fidai, Peter Pytel, and Bakhtiar Yamini.
    • Section of Neurosurgery, University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA.
    • World Neurosurg. 2019 May 1; 125: 32-36.

    BackgroundDifferential diagnosis of sellar masses includes adenoma, meningioma, craniopharyngioma, and metastasis. Primary paraganglioma is seldom considered. We present a case of this unique pathology, review the relevant literature, and compile a compendium of immunohistochemical characteristics for use as a resource.Case DescriptionA 73-year-old woman presented to the hospital with visual changes in her left hemifield. Noncontrast head computed tomography demonstrated a large sellar mass with suprasellar extension and displacement of the optic chiasm (diameter of 3.1 cm). Magnetic resonance imaging was unobtainable owing to an incompatible pacemaker. Computed tomography characterization was most consistent with a macroadenoma. Given the acute visual decline, surgical decompression via an endonasal transsphenoidal route was performed without complication. A diagnosis of paraganglioma was made based on histopathology. Following resection, the patient's visual field deficit improved. Computed tomography body imaging was negative for a metastatic origin.ConclusionsParaganglioma is a rare but potential differential diagnosis to consider when evaluating sellar masses.Copyright © 2019 Elsevier Inc. All rights reserved.

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