• Gülpembe Bozkurt, Federico Leone, Alberto Daniele Arosio, Dehgani Mobaraki Puya P Division of Otorhinolaryngology, Gubbio-Gualdo Tadino Hospital, USL Umbria 1, Italy., Hassan Ahmed Elhassan, Nurullah Seyhun, Mario Turri-Zanoni, Paolo Castelnuovo, and Paolo Battaglia.
• Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy. Electronic address: gptalayhan@gmail.com.
• World Neurosurg. 2019 Apr 28.

BackgroundEndoscopic endonasal anterior skull base malignant sinonasal tumor resection and reconstruction remains a challenge. We describe our septal flip flap (SFF) reconstruction, a new surgical technique for repairing anterior skull base defects and report our outcomes.MethodsWe retrospectively reviewed the clinical data of 24 patients who underwent skull base reconstruction using a SFF following endoscopic resection with transnasal craniectomy. We raise the SFF from the contralateral nasal septum based on the septal branches of the anterior and posterior ethmoidal arteries; the SFF is then rotated laterally for anterior skull base reconstruction after transnasal resection with craniectomy.ResultsThe SFF was used for multiple tumor types including, most commonly, intestinal-type adenocarcinoma, followed by olfactory neuroblastoma, squamous cell carcinoma, sinonasal undifferentiated carcinoma, and other types. All of the cases had either preoperative or postoperative radiation therapy. All flaps remained viable postoperatively. Postoperatively, nasal crusting was significantly reduced with faster healing of the surgical cavity.ConclusionsThe SFF adds to the clinical armamentarium the opportunity to provide vascularized mucosal coverage extending from the frontal recess back to the planum sphenoidalis. The use of SFF requires careful consideration when dealing with paranasal sinus cancers so as not to infringe oncologic principles.Copyright © 2019 Elsevier Inc. All rights reserved.

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