• Xianghui Liu, Jun Zhou, Bin Shen, Dezhou Sun, Zhiying Zhang, Honglei Li, and Jian Zhang.
• Department of Neurosurgery, Dezhou People's Hospital, Dezhou, China.
• World Neurosurg. 2019 Oct 1; 130: 165-169.

BackgroundOssified chronic subdural hematoma (CSH) associated with neoplasm has rarely been reported in the literature. We describe a patient with ossified CSH and underlying large B-cell lymphoma and discuss the relationship between lymphoma and CSH, emphasizing clinical characteristics, tumorigenic mechanism, and histopathologic analysis.Case DescriptionA 46-year-old man with a history of alcohol abuse and a right frontotemporoparietal and left frontal ossified CSH that was diagnosed 2 years previously presented with headache and memory loss over 6 days. The patient was being followed with serial imaging, which showed the static state of the mass and no other lesions 7 months before admission. He underwent right frontotemporoparietal craniectomy to remove the ossified CSH and tumor. When the bone was lifted and the thin dura was opened, a hard, thick, ossified capsule was observed. No apparent tumor invasion was noted in the skull or epidural space. Despite refusing further chemotherapy and radiation therapy, the patient has been disease-free and working for 5 years.ConclusionsBased on reported cases and relevant literature, large B-cell lymphoma may be associated with ossified CSH.Copyright © 2019 Elsevier Inc. All rights reserved.

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