• Randall C Edgell, Osama O Zaidat, Rishi Gupta, Alex Abou-Chebl, Italo Linfante, Andrew Xavier, Raul Nogueira, Amer Alshekhlee, Jundaid Kalia, Vahid Etezadi, Nima Aghaebrahim, and Tudor Jovin.
• Society of Vascular and Interventional Neurology Research Consortium at Saint Louis University, Department of Neurology and Psychiatry, Saint Louis, MO 63104. USA.
• J Neuroimaging. 2013 Apr 1;23(2):170-4.

PurposeTo assess the safety and efficacy of vertebral artery origin angioplasty and stenting for stroke prevention in a multicenter clinical experience.MethodsPatients with symptomatic vertebral artery origin stenosis (VAOS) were gathered from the Society of Vascular and Interventional Neurology Research Consortium. Demographic, clinical, and procedural data were collected. The main outcome measure was procedural and peri-procedural risks of stroke, transient ischemic attack (TIA), or death at 1 and 3 months. Logistic regression analysis was used to assess covariates associated with future restenosis.ResultsA total of 148 patients were included with mean age of 66.2 ± 11.5; 74% men and 77% Caucasian. One patient (.8%) had a stroke at 1 month and 5 of 96 (5.2%) patients had TIA at 3 months. There were no immediate procedural events or deaths. The mean angiographic pre-treatment stenosis was 80.5 ± 12.7%, which was reduced to 5.3 ± 9.1% after stent deployment. Follow-up angiography showed 15.5% of patients had significant restenosis (≥50%). Predictors of restenosis included age (OR 3.08; 95% CI 1.01, 9.41) and smoking (OR 3.10; 95% CI 1.12, 8.64).ConclusionsEndovascular intervention of VAOS is associated with low peri-procedural complication rates. Restenosis remains a concern; age and smoking predicted future restenosis.Copyright © 2011 by the American Society of Neuroimaging.

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