• Neuroimaging Clin. N. Am. · Nov 2012

    Review

    Fungal infections of the central nervous system.

    • Mahan Mathur, Carl E Johnson, and Gordon Sze.
    • Department of Radiology, Yale University Medical Center, New Haven, CT 06510, USA. mahan.mathur@gmail.com
    • Neuroimaging Clin. N. Am. 2012 Nov 1; 22 (4): 609-32.

    AbstractFungal infections of the central nervous system (CNS) frequently occur in the immunocompromised or debilitated host. Imaging findings are non-specific but may be organized into extra-axial, parenchymal, and vascular categories. Furthermore, knowledge of fungal morphology may predict the imaging manifestations with large, hyphal species having a predilection for brain parenchymal involvement, while small, unicellular organisms typically result in meningitis. Advanced imaging techniques such as diffusion-weighted imaging, MR perfusion and MR spectroscopy, when combined with clinical findings, may help in differentiating fungal disease from other mimckers such as pyogenic infection or cystic metastases.Copyright © 2012 Elsevier Inc. All rights reserved.

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