• Neuroimaging Clin. N. Am. · May 2013

    Review

    Childhood central nervous system vasculitis.

    • Mahendranath Moharir, Manohar Shroff, and Susanne M Benseler.
    • Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
    • Neuroimaging Clin. N. Am.. 2013 May 1;23(2):293-308.

    AbstractInflammatory brain diseases in childhood are underrecognized and lead to devastating yet potentially reversible deficits. New-onset neurologic or psychiatric deficits in previously healthy children mandate an evaluation for an underlying inflammatory brain disease. Distinct disease entities, such as central nervous system (CNS) vasculitis, are now being increasingly reported in children. Clinical symptoms, initial laboratory test, and neuroimaging studies help to differentiate between different causes; however, more invasive tests, such as lumbar puncture, conventional angiography, and/or brain biopsy, are usually necessary before the start of treatment. This article focuses on childhood CNS vasculitis.Copyright © 2013 Elsevier Inc. All rights reserved.

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