• Arch Orthop Trauma Surg · Jul 2001

    The contribution of vitamin C to healing of experimental fractures.

    • C Yilmaz, E Erdemli, H Selek, H Kinik, M Arikan, and B Erdemli.
    • Department of Orthopaedics and Traumatology, University of Ankara Medical School, Turkey. cyilmaz@doctor.com
    • Arch Orthop Trauma Surg. 2001 Jul 1; 121 (7): 426-8.

    AbstractThe benefits of various minerals and vitamins on fracture healing have been demonstrated in animal models. Vitamin C is an essential substance in fracture healing but has not been studied previously on an experimental basis. Sixteen rats were grouped randomly into control and vitamin C-supplemented groups. The right tibias of all rats were fractured by digital manipulation. One group received single high dose of vitamin C intramuscularly. On the 5th, 10th, 15th, and 20th days, two rats from each group were killed and the tibias examined under light microscopy. It was seen that the vitamin C-supplemented group went through the stages of fracture healing faster compared with the control group.

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