• Clin J Pain · Dec 2001

    Case Reports

    A case of a methadone-induced movement disorder.

    • J D Clark and J Elliott.
    • Veterans Affairs Palo Alto Health Care System, California 94304, USA. djclark@stanford.edu
    • Clin J Pain. 2001 Dec 1; 17 (4): 375-7.

    ObjectiveTo increase awareness of the possibility of opioid induced movement disorders.SettingA university-affiliated Veterans Affairs Hospital.PatientA patient with upper extremity pain due to complex regional pain syndrome type I (reflex sympathetic dystrophy).InterventionsAttempted pain control with methadone.Results And ConclusionsAfter failing many attempts at control, the authors were able to provide their patient significant pain relief from her complex regional pain syndrome type I using methadone. Unfortunately, the patient eventually developed a movement disorder, characterized by tremor, choreiform movements, and a gait abnormality, probably related to this opioid. The authors conclude that, while this type of movement disorder is uncommon, clinicians need to be aware of opioid-induced movement disorders, because they are disturbing to patients and often easily treated.

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