• World Neurosurg · Feb 2020

    Case Reports

    Thoracic Intradural Extramedullary Ependymoma with anaplastic transformation: A case report and discussion.

    • Christopher Yusuf Akhunbay-Fudge, Arundhati Chakrabarty, Christopher Derham, and Debasish Pal.
    • Department of Neurosurgery, Leeds Teaching Hospitals NHS Trust, Leeds, England. Electronic address: Christopher.akhunbay-fudge@nhs.net.
    • World Neurosurg. 2020 Feb 1; 134: 549-554.

    BackgroundIntradural extramedullary spinal ependymomas arising from outside the region of the conus medullaris are rare clinical entities, and anaplastic transformation of these lesions is even more exceptional.Case DescriptionWe report on a case of an intradural extramedullary T5-T6 ependymoma that underwent gross total resection. Histologic analysis of the initial tumor revealed a World Health Organization grade 2 ependymoma. Two years after initial surgical resection, there was radiologic recurrence and a re-do resection was performed with subsequent spinal stabilization. Histologic analysis of the recurrent tumor revealed a World Health Organization grade 3 ependymoma. After surgery the patient received radiotherapy, and he remains disease free at 2 years following his second surgery. In addition, we employed carbon fiber screws and rods for stabilization in his second operation to reduce artefact on follow-up imaging.ConclusionsWe advocate that primary spinal ependymomas should be within the differential of intradural extramedullary lesions arising outside the region of the conus medullaris.Copyright © 2019 Elsevier Inc. All rights reserved.

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