• Kai Ma, Jintai Yu, Wei Shao, Xijia Xu, Zhiqiang Zhang, and Daoqiang Zhang.
• Department of Computer Science and Technology, Nanjing University of Aeronautics and Astronautics, MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing, Jiangsu Province 210016, China.
• Neuroscience. 2020 Jan 15; 425: 39-48.

AbstractPsychopath and neuropath often exhibit similar symptoms in clinical functional performances. However, few studies ever demonstrate the existence of overlapped brain functional mechanism between neurological and psychiatric disorders. Accordingly, in this paper, we have made an attempt to verify the existence of functional overlaps among neurological and psychiatric disorders through brain network analysis. Specifically, our findings suggest that functional overlaps exist in mild cognitive impairment (MCI), Alzheimer's disease (AD) and major depressive disorder (MDD), as well as in epilepsy, attention deficit hyperactivity disorder (ADHD) and schizophrenia. In these overlapped functions, we also find that the brain regions of neuropsychopathic disorders exhibit different cooperative patterns at different levels of brain activities. For example, strong-strong cooperative patterns were observed at high levels of brain activities in epilepsy, ADHD and schizophrenia.Copyright © 2019 IBRO. Published by Elsevier Ltd. All rights reserved.

24 keywords...

hide…