Solitary metastatic melanoma of the pituitary gland: Report of

World Neurosurg · Jul 2020

Review Case Reports

Solitary metastatic melanoma of the pituitary gland: Report of two cases and Literature review.

Pituitary melanoma metastases (PMMs) are extremely rare and only a few cases are reported in the literature. PMMs can grow rapidly and present local invasiveness, leading to acute onset of neurological symptoms such as headache, visual and oculomotion disorders or endocrinological signs such as diabetes insipidus and hypopituitarism, and can be life-threatening. For this reason, PMMs must be recognized and treated promptly. ⋯ The authors present 2 cases of PMMs managed at their institution, performing a review of the dedicated literature and analyzing current therapeutic strategies.

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- Pier Paolo Mattogno, Martina Giordano, Quintino Giorgio D'Alessandris, Omar Ktari, Antonella Giampietro, Mario Rigante, Marco Gessi, Alessandro Olivi, and Liverana Lauretti.
- Department of Neurosurgery, Fondazione Policlinico Gemelli IRCCS, Università Cattolica del Sacro Cuore - Roma, Rome, Italy. Electronic address: pierpaolo.mattogno@policlinicogemelli.it.
- World Neurosurg. 2020 Jul 1; 139: 378381378-381.
BackgroundPituitary melanoma metastases (PMMs) are extremely rare and only a few cases are reported in the literature. PMMs can grow rapidly and present local invasiveness, leading to acute onset of neurological symptoms such as headache, visual and oculomotion disorders or endocrinological signs such as diabetes insipidus and hypopituitarism, and can be life-threatening. For this reason, PMMs must be recognized and treated promptly.Case DescriptionThe authors present 2 cases of PMMs managed at their institution, performing a review of the dedicated literature and analyzing current therapeutic strategies.Copyright © 2020 Elsevier Inc. All rights reserved.

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Solitary metastatic melanoma of the pituitary gland: Report of two cases and Literature review.

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