Circulation journal : official journal of the Japanese Circulation Society
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Multicenter Study
Active infective endocarditis: management and risk analysis of hospital death from 24 years' experience.
This study was performed to identify risk factors for hospital death in patients with acute and active infective endocarditis (AAIE) after surgical intervention. ⋯ In AAIE, early surgical intervention is advisable before the occurrence of complications such as root abscess and CHF, particularly before the onset of CHF.
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Little has been published regarding the association between perioperative stress response and clinical outcomes after off-pump coronary artery bypass surgery (OPCAB). The role of perioperative stress response in postoperative inflammatory complications (PIC) in patients undergoing OPCAB was assessed. ⋯ Patients with PIC after OPCAB have significantly increased preoperative cortisol and cortisol on the first postoperative day. Intraoperative cortisol release was significantly correlated with hemodynamic changes. The neurohormonal environment and inflammatory response during and after beating-heart surgery should be further explored.
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The dual goals of low-density lipoprotein-cholesterol (LDL-C) and C-reactive protein (CRP) reduction are important for secondary prevention of cardiovascular disease. However, the relevant factors of subclinical inflammation in patients with optimal LDL-C were not clearly demonstrated. This study sought to test the hypothesis that the metabolic syndrome (MetS) is associated with subclinical inflammation in patients achieving optimal LDL-C. ⋯ MetS is well associated with higher CRP concentrations in patients who achieved optimal LDL-C levels.
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In the case of stent thrombosis and resistance to clopidogrel, choices of an alternative drug remain limited. In 2 cases of subacute stent thrombosis associated with clopidogrel resistance, an adequate response was obtained in these patients after repeated loading doses of clopidogrel.
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To investigate 576 patients undergoing coronary artery bypass grafting (CABG) and to evaluate independent high risk factors of postoperative hypoxemia following CABG. ⋯ Preoperative chronic pulmonary diseases, preoperative acute myocardial infarction, and preoperative diabetes are 3 independent risk factors of postoperative hypoxemia following CABG.