Journal of thrombosis and haemostasis : JTH
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J. Thromb. Haemost. · Jan 2009
Randomized Controlled Trial Multicenter StudyDalteparin for the prevention of recurrence of placental-mediated complications of pregnancy in women without thrombophilia: a pilot randomized controlled trial.
The role of anticoagulants for the prevention of placental-mediated pregnancy complications is uncertain. ⋯ In this pilot study, dalteparin is effective in decreasing the recurrence of placental-mediated complications in women without thrombophilia. Our results require confirmation in further randomized trials.
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J. Thromb. Haemost. · Jan 2009
Review Historical ArticleThe impact of fibrinolytic therapy for ST-segment-elevation acute myocardial infarction.
As privileged witnesses of the initiation and widespread use of reperfusion therapy the authors review the history of fibrinolytic therapy and of tissue-plasminogen activator (t-PA) more particularly and the current indications for its use in the era of mechanical reperfusion.
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J. Thromb. Haemost. · Jan 2009
Guidelines and the use of inferior vena cava filters: a review of an institutional experience.
Based on the American College of Chest Physicians 2004 antithrombotic therapy for venous thromboembolism (VTE) and the Eastern Association for the Surgery of Trauma 2002 guidelines, placement of an inferior vena cava (IVC) filter is indicated in patients who either have, or are at high risk for, VTE, but have a contraindication or failure of anticoagulation. Our aim is to compare clinical characteristics and outcomes of patients receiving IVC filters within-guidelines (WG) and outside-of-guidelines (OOG). ⋯ Our data do not support the use of an IVC filter outside of guidelines in patients without prior VTE who can tolerate anticoagulation because of the low risk of developing PE.