Circulation
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Randomized Controlled Trial Multicenter Study
Cognitive function in survivors of out-of-hospital cardiac arrest after target temperature management at 33°C versus 36°C.
Target temperature management is recommended as a neuroprotective strategy after out-of-hospital cardiac arrest. Potential effects of different target temperatures on cognitive impairment commonly described in survivors have not been investigated sufficiently. The primary aim of this study was to evaluate whether a target temperature of 33°C compared with 36°C was favorable for cognitive function; the secondary aim was to describe cognitive impairment in cardiac arrest survivors in general. ⋯ URL: http://www.clinicaltrials.gov. Unique identifier: NCT01946932.
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Multicenter Study Comparative Study Observational Study
Sex differences in reperfusion in young patients with ST-segment-elevation myocardial infarction: results from the VIRGO study.
Sex disparities in reperfusion therapy for patients with acute ST-segment-elevation myocardial infarction have been documented. However, little is known about whether these patterns exist in the comparison of young women with men. ⋯ Young women with ST-segment-elevation myocardial infarction are less likely to receive reperfusion therapy and more likely to have reperfusion delays than similarly aged men. Sex disparities are more pronounced among patients transferred to percutaneous coronary intervention institutions or who received fibrinolytic therapy.