Circulation
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Randomized Controlled Trial Multicenter Study
Cognitive function in survivors of out-of-hospital cardiac arrest after target temperature management at 33°C versus 36°C.
Target temperature management is recommended as a neuroprotective strategy after out-of-hospital cardiac arrest. Potential effects of different target temperatures on cognitive impairment commonly described in survivors have not been investigated sufficiently. The primary aim of this study was to evaluate whether a target temperature of 33°C compared with 36°C was favorable for cognitive function; the secondary aim was to describe cognitive impairment in cardiac arrest survivors in general. ⋯ URL: http://www.clinicaltrials.gov. Unique identifier: NCT01946932.