The journal of trauma and acute care surgery
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J Trauma Acute Care Surg · May 2015
Randomized Controlled Trial Multicenter Study Comparative StudyAn open, parallel, randomized, comparative, multicenter investigation evaluating the efficacy and tolerability of Mepilex Ag versus silver sulfadiazine in the treatment of deep partial-thickness burn injuries.
Partial-thickness burns are among the most frequently encountered types of burns, and numerous dressing materials are available for their treatment. A multicenter, open, randomized, and parallel study was undertaken to determine the efficacy and tolerability of silver sulfadiazine (SSD) compared with an absorbent foam silver dressing, Mepilex Ag, on patients aged between 5 years and 65 years with deep partial-thickness thermal burn injuries (2.5-25% total body surface area). ⋯ Therapeutic study, level III.
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J Trauma Acute Care Surg · May 2015
Randomized Controlled Trial Multicenter StudyThe impact of tranexamic acid on mortality in injured patients with hyperfibrinolysis.
In 2011, supported by data from two separate trauma centers, we implemented a protocol to administer tranexamic acid (TXA) in trauma patients with evidence of hyperfibrinolysis (HF) on admission. The purpose of this study was to examine whether the use of TXA in patients with HF determined by admission rapid thrombelastography was associated with improved survival. ⋯ Therapeutic study, level IV.
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J Trauma Acute Care Surg · May 2015
Multicenter StudyFeasibility and utility of population-level geospatial injury profiling: prospective, national cohort study.
Geospatial analysis is increasingly being used to evaluate the design and effectiveness of trauma systems, but there are no metrics to describe the geographic distribution of incidents. The aim of this study, therefore, was to evaluate the feasibility and utility of using spatial analysis to characterize, at scale, the geospatial profile of an injured population. ⋯ This study demonstrates the feasibility and power of describing the geographic distribution of a group of injured patients. The methodology described has potential application for injury surveillance and trauma system design and evaluation.
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J Trauma Acute Care Surg · May 2015
Multicenter StudyTrends in pediatric spleen management: Do hospital type and ownership still matter?
Nonoperative management of traumatic blunt splenic injury is preferred over splenectomy because of improved outcomes and reduced complications. However, variability in treatment is previously reported with respect to hospital profit types and ownership. ⋯ Epidemiologic and prognostic study, level III.
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J Trauma Acute Care Surg · May 2015
Multicenter StudyDoes unit designation matter? A dedicated trauma intensive care unit is associated with lower postinjury complication rates and death after major complication.
Recent data suggest that specialty intensive care units (ICUs) have outcomes better than those of mixed ICUs. The cause for this apparent discrepancy has not been well established. We hypothesized that trauma patients admitted to a dedicated trauma ICU (TICU) would have a lower complication rate as well as death after complication (failure to rescue [FTR]). ⋯ Prognostic study, level III.