The journal of trauma and acute care surgery
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J Trauma Acute Care Surg · May 2015
Randomized Controlled Trial Multicenter Study Comparative StudyAn open, parallel, randomized, comparative, multicenter investigation evaluating the efficacy and tolerability of Mepilex Ag versus silver sulfadiazine in the treatment of deep partial-thickness burn injuries.
Partial-thickness burns are among the most frequently encountered types of burns, and numerous dressing materials are available for their treatment. A multicenter, open, randomized, and parallel study was undertaken to determine the efficacy and tolerability of silver sulfadiazine (SSD) compared with an absorbent foam silver dressing, Mepilex Ag, on patients aged between 5 years and 65 years with deep partial-thickness thermal burn injuries (2.5-25% total body surface area). ⋯ Therapeutic study, level III.
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J Trauma Acute Care Surg · May 2015
Randomized Controlled Trial Multicenter StudyThe impact of tranexamic acid on mortality in injured patients with hyperfibrinolysis.
In 2011, supported by data from two separate trauma centers, we implemented a protocol to administer tranexamic acid (TXA) in trauma patients with evidence of hyperfibrinolysis (HF) on admission. The purpose of this study was to examine whether the use of TXA in patients with HF determined by admission rapid thrombelastography was associated with improved survival. ⋯ Therapeutic study, level IV.