The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Aug 2009
Multicenter StudyPhenotype of atopic dermatitis subjects with a history of eczema herpeticum.
A subset of subjects with atopic dermatitis (AD) are susceptible to serious infections with herpes simplex virus, called eczema herpeticum, or vaccina virus, called eczema vaccinatum. ⋯ Subjects with AD in whom eczema herpeticum develops have more severe T(H)2-polarized disease with greater allergen sensitization and more commonly have a history of food allergy, asthma, or both. They are also much more likely to experience cutaneous infections with S. aureus or molluscum contagiosum.