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The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · May 2014
Randomized Controlled Trial Multicenter StudyObesity and adiposity indicators, asthma, and atopy in Puerto Rican children.
Whether adiposity indicators other than body mass index (BMI) should be used in studies of childhood asthma is largely unknown. The role of atopy in "obese asthma" is also unclear. ⋯ Adiposity indicators are associated with asthma, asthma severity/control, and atopy in Puerto Rican children. Atopy significantly mediates the effect of adiposity on asthma outcomes. Longitudinal studies are needed to further investigate the causal role, if any, of adiposity distribution and atopy on "obese asthma" in childhood.