Anesthesiology

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• Anesthesiology · Dec 2013

  Critical Role of Interleukin-11 in Isoflurane-mediated Protection against Ischemic Acute Kidney Injury in Mice.

  Isoflurane releases renal tubular transforming growth factor-β1 (TGF-β1) and protects against ischemic acute kidney injury. Recent studies suggest that TGF-β1 can induce a cytoprotective cytokine interleukin (IL)-11. In this study, the authors tested the hypothesis that isoflurane protects against ischemic acute kidney injury by direct induction of renal tubular IL-11 synthesis. ⋯ In this study, the authors suggest that isoflurane induces renal tubular IL-11 via TGF-β1 signaling to protect against ischemic acute kidney injury.

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• Anesthesiology · Dec 2013

  Editorial Comment

  Complications of Laryngeal Masks in Children: Big Data Comes to Pediatric Anesthesia.

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• Anesthesiology · Dec 2013

  Editorial Comment

  Equivalent Efficacy of Hydroxyethyl Starch 130/0.4 and Human Serum Albumin: If Nothing Is the Same, Is Everything Different? The Importance of Context in Clinical Trials and Statistics.

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• Anesthesiology · Dec 2013

  Editorial Comment

  "Seeing" how our drugs work brings translational added value.

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• Anesthesiology · Dec 2013

  Editorial Comment

  Neural and Immune Consequences of Traumatic Brain Injury: Does Propofol Reduce the Impact?

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