Anesthesiology
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Randomized Controlled Trial
Increased Risk of Intraoperative Awareness in Patients with a History of Awareness.
Patients with a history of intraoperative awareness are five-times more likely to experience awareness than those without.
pearl -
Randomized Controlled Trial
Lidocaine Patch (5%) in Treatment of Persistent Inguinal Postherniorrhaphy Pain: A Randomized, Double-blind, Placebo-controlled, Crossover Trial.
Evidence-based pharmacological treatment options for patients with persistent inguinal postherniorrhaphy pain are lacking. ⋯ Lidocaine patch treatment did not reduce combined resting and dynamic pain ratings compared with placebo in patients with severe, persistent inguinal postherniorrhaphy pain.
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Randomized Controlled Trial Multicenter Study Comparative Study
Six Percent Hydroxyethyl Starch 130/0.4 (Voluven®) versus 5% Human Serum Albumin for Volume Replacement Therapy during Elective Open-heart Surgery in Pediatric Patients.
Although 5% albumin (human serum albumin [HSA]) is widely used in cardiac surgery children, synthetic colloids may provide a valuable alternative. This study compared 6% hydroxyethyl starch (HES) 130/0.4 with HSA for volume replacement in this population. ⋯ In pediatric cardiac surgery, HES showed equivalence to HSA with regard to volume replacement therapy in children aged from 2 to 12 yr. Although there was no suggestion of an imbalance of safety measures between HES and HSA, the study was not powered to provide any firm conclusions about safety of tetrastarch in this population.