Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Feb 2025
Review Meta AnalysisChildhood asthma and mould in homes-A meta-analysis.
Asthma is a multifaceted and multicausal disease. Childhood asthma is strongly influenced by genetic traits and is characterized by hyperreactivity of the airways so that also unspecific triggers including moulds can trigger an asthma attack. Therefore, it is undisputed that moulds in the home can cause asthma attacks in asthmatic children. ⋯ The cohort studies also showed no publication bias but substantial heterogeneity (I2 = 60.5, p = 0.005). Heterogeneity could be partly explained by percentage of male children, age of participants, and publication year, but was not affected by study quality. In conclusion, living in mouldy homes during childhood seems to increase the risk of later developing bronchial asthma.
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Wien. Klin. Wochenschr. · Sep 2024
Review Meta AnalysisThe prevalence of presbyphagia in older adults: a systematic review and meta-analysis.
Presbyphagia is defined as structural, physiological and innervational alterations in the swallowing process as a result of aging and is considered to be involved in the etiology of dysphagia. This systematic review and meta-analysis aimed to estimate the prevalence of presbyphagia in older adults without disease-related dysphagia. ⋯ Although the pooled prevalence of presbyphagia in older adults was 17.3%, the lack of large representative studies limited the interpretation of these findings. In the future, further large studies that diagnose presbyphagia using standardized assessment tools would facilitate new avenues to reduce the risk of dysphagia in older adults.
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Wien. Klin. Wochenschr. · May 2024
Review Meta AnalysisSame-day discharge after percutaneous coronary procedures-Structured review and comprehensive meta-analysis.
Percutaneous coronary intervention is a well-established revascularization strategy for patients with coronary artery disease. The safety and feasibility of performing these procedures on a same-day discharge basis for selected patients has been studied in a large number of mostly nonrandomized trials. An up to date literature review should focus on trials with radial access, representing the current standard for coronary procedures in Austria and other European countries. ⋯ Outcome data from same-day discharge coronary intervention trials with radial access confirm the robust safety profile showing no increase in the risk of major adverse events compared to overnight stay.
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Wien. Klin. Wochenschr. · Aug 2023
Review Meta AnalysisGlobal prevalence of constipation in older adults: a systematic review and meta-analysis.
Constipation is one of the most common functional disorders of the gastrointestinal tract in older adults. To date, no systematic review or previous meta-analysis has estimated the global prevalence of constipation in older adults. The prevalence of this disorder has been reported differently in different studies; therefore, this study aims to systematically review the publications and to perform a meta-analysis of the prevalence of constipation in older adults. ⋯ The results suggest that health policymakers should pay more attention to the prevention of constipation in older adults, including raising public awareness to the importance of nutrition and diet and physical activity in older adults.
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Wien. Klin. Wochenschr. · Nov 2022
Meta AnalysisInflammatory bowel disease and risk of coronary heart disease : A Mendelian randomization study.
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), has been reported to be associated with an increased risk of coronary heart disease (CHD); however, the causal link between IBD and CHD is unclear. We performed Mendelian randomization (MR) analysis to investigate the association between genetically predicted IBD and CHD risk. ⋯ The results of this study suggested that genetically predicted IBD may have no causal effect on CHD risk in a population with European ancestry.