Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Jan 2003
Review[New insights on the effects of hormone replacement therapy on the breast tissue and the orgnaism].
Within the last fifteen to twenty years extensive discussions were held about advantages and disadvantages of postmenopausal hormone replacement therapy. Basing on recent data from prospectively randomized studies the long-term application of a combined estrogen-gestagen therapy for general prophylaxis cannot be recommended. Ongoing studies are expected to provide sufficient data to determine regimens for the prevention of osteoporosis, development of cancer, and cardiovascular diseases.