Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · May 2004
Randomized Controlled Trial Comparative Study Clinical TrialHuman albumin and starch administration in critically ill patients: a prospective randomized clinical trial.
To determine whether intravenous infusion of either human albumin or hydroxyethyl-starch (HES) in hypo-albuminemic critically ill may lead to an increase in colloid osmotic pressure and to a better clinical outcome, i.e. lower mortality and fewer complications, compared to fluid replacement with normal saline. ⋯ Raising colloid osmotic pressure with human albumin in hypoalbuminemic patients is not associated with improvement of the clinical outcome.