Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Nov 2022
Meta AnalysisInflammatory bowel disease and risk of coronary heart disease : A Mendelian randomization study.
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), has been reported to be associated with an increased risk of coronary heart disease (CHD); however, the causal link between IBD and CHD is unclear. We performed Mendelian randomization (MR) analysis to investigate the association between genetically predicted IBD and CHD risk. ⋯ The results of this study suggested that genetically predicted IBD may have no causal effect on CHD risk in a population with European ancestry.