Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Nov 2023
An alternative treatment option in older adults with knee osteoarthritis : Genicular nerve pulsed radiofrequency.
Osteoarthritis (OA), including knee OA (KOA), is an important cause of morbidity and disability in older adults. Pain management plays a major role in the treatment of KOA for pain relief and knee function improvement. Ultrasound-guided genicular nerve pulsed radiofrequency therapy is an effective, safe, nonradiative, and easily applicable treatment modality in older adults with KOA. It has a positive effect on geriatric syndromes, especially polypharmacy.
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Wien. Klin. Wochenschr. · Nov 2023
Multicenter StudyIs the prognosis of traumatic critically ill pediatric patients predictable? : A multicenter retrospective analysis.
In this retrospective study the effects of the neutrophil to lymphocyte ratio (NLR), monocyte to lymphocyte ratio (MLR), mean platelet volume to platelet count ratio (MPV/PC) values as well as C‑reactive protein (CRP) and procalcitonin (PCT) levels on the severity and mortality in critically ill child trauma cases were evaluated. ⋯ The NLR, MLR, and MPV/PC values do not predict the severity of the trauma in children. In children with severe trauma, low MLR and high MPV/PC values can be used to predict mortality.
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Wien. Klin. Wochenschr. · Nov 2023
[Hereditary angioedema due to C1-inhibitor deficiency, a national disease management programme].
Hereditary angioedema (HAE) is a rare, painful, disabling and potentially fatal disease, where early diagnosis and effective treatment are critical. These Austrian guidelines for the diagnosis and management of HAE provide instructions and advice on the state of the art management of HAE in Austria in contrast to global guidelines, where the situation of all countries worldwide must be taken into account. Our goal is to help Austrian physicians to consider HAE as a differential diagnosis with corresponding symptoms, to make rational decisions for the diagnosis and management of HAE with C1-inhibitor deficiency (type 1 or type 2). The guidelines provide information on common and important clinical symptoms, diagnostic methods, treatment modalities, available HAE-specific medications in Austria and last but not least to motivate physicians to refer patients to HAE centers for confirmation of the diagnosis and adequate treatment decisions.