Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Jan 2022
The effect of biofeedback on smoking cessation-a systematic short review.
The aim of this systematic review was to focus on the effect of biofeedback on smoking cessation. ⋯ The results of the present review suggest that biofeedback/neurofeedback training might facilitate smoking cessation by changing behavioral outcomes. Although the investigated studies contained heterogeneous methodologies, they showed interesting approaches that could be further investigated and elaborated. To improve the scientific evidence, prospective randomized controlled trials are needed to investigate biofeedback/neurofeedback in clinical settings for smoking cessation.
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Wien. Klin. Wochenschr. · Jan 2022
Increase in testosterone levels is related to a lower risk of conversion of prediabetes to manifest diabetes in prediabetic males.
Testosterone plays an important role in the regulation of glucose metabolism. While earlier studies have shown that it has a protective effect in males, unfavorable effects of testosterone on glucose metabolism have been reported in females; however, whether there is a sex-specific relationship between testosterone and glucose metabolism in patients with prediabetes has not been investigated in detail hitherto. ⋯ The increase of testosterone levels in males was related to a more favorable glucose metabolism, including lower HbA1c, lower stimulated glucose levels and higher insulin sensitivity; however, in prediabetic females, testosterone was not related to glucose metabolism.
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Wien. Klin. Wochenschr. · Jan 2022
CDC25c expression in patients with myelofibrosis is associated with stronger myeloproliferation and shorter overall survival.
Cell division cycle 25c (CDC25c) is a gene coding a phosphatase controlling entry into mitosis upon activation through Polo-like kinase 1 (PLK1) and serves as a key regulator of cell division. The CDC25c was reported to be dysregulated in some malignant diseases, but its role in myelofibrosis has not yet been elucidated. ⋯ Our data suggest that higher CDC25c expression is associated with more proliferative phenotype of myelofibrosis and is prognostic of worse survival. Future studies investigating these interesting associations are warranted.