Wiener klinische Wochenschrift
-
Wien. Klin. Wochenschr. · May 2003
HIV infection and sputum-culture conversion in patients diagnosed with Mycobacterium tuberculosis: a population-based study.
To estimate the effect of human immunodeficiency virus infection on treatment outcome of anti-tuberculosis therapy at the population level. ⋯ Response to anti-tuberculosis therapy was significantly less favorable in HIV-infected than in HIV-uninfected tuberculosis patients. The importance of longer and closer monitoring of tuberculosis treatment in HIV-positive patients is highlighted.
-
Wien. Klin. Wochenschr. · May 2003
Case ReportsSpontaneous dissecting aneurysm of the coronary artery. A rare cause of myocardial infarction and sudden death.
Spontaneous dissecting aneurysm of the coronary artery (SDACA) not associated with aortic aneurysm or trauma is a very rare cause of myocardial ischemia. It has a higher prevalence in otherwise healthy women, especially in the peri- and postpartum period. In 80-90% of cases the diagnosis of SDACA is confirmed at autopsy, as the majority of patients present with acute myocardial infarction or sudden death. ⋯ Acute myocardial infarction was present in the posterior wall of the left cardiac ventricle. SDACA is an unpredictable condition and prompt diagnosis and life-saving procedures--either surgical or conservative--are rarely successful. We report a very rare disease documented in only 108 cases according to the English-language literature accessible to us.
-
Wien. Klin. Wochenschr. · May 2003
Osteoprotegerin serum levels in women: correlation with age, bone mass, bone turnover and fracture status.
Pre-clinical data have shown that osteoprotegerin (OPG) inhibits osteoclast function and therefore plays an important role in bone remodelling. This study aimed to evaluate the clinical value of serum OPG. Do higher OPG serum levels reflect decreased bone resorption and perhaps higher bone mass in women? Serum OPG levels were measured in 177 healthy women (aged 17-85 years) and in 48 untreated patients (mean age 71 +/- 5) with established osteoporosis, and related to age, bone mass, markers of bone turnover and, in the case of patients with osteoporosis, to pre-existing vertebral fractures. ⋯ In patients with osteoporosis, however, OPG correlated strongly with markers of bone turnover; this may point toward a higher level of RANKL/OPG expression in these patients. Finally, low OPG serum levels seem to be associated with vertebral fractures. We hypothesise that low OPG levels in preset conditions of bone turnover may indicate a higher risk of fracture in patients with osteoporosis.
-
To update our published systematic review of clinical trials of distant healing. ⋯ Since the publication of our previous systematic review in 2000, several rigorous new studies have emerged. Collectively they shift the weight of the evidence against the notion that distant healing is more than a placebo.
-
Wien. Klin. Wochenschr. · Apr 2003
Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial[Evaluation of a new insulating system for infusion solutions in preclinical trauma therapy: a prospective, randomized study].
Infusion of cold fluids in a patient leads to a reduction of core temperature and subsequently worsens hypothermia. We evaluated the efficacy of a newly developed self-warming insulation device for use in pre-hospital rescue. ⋯ Our data show that even pre-warmed infusions from a warming box cool down considerably before they can be given to the patient. A self-warming insulation device can stabilize infusion temperature even under extreme conditions of prehospital trauma care.