Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Mar 2010
ReviewHypoxic hepatitis - epidemiology, pathophysiology and clinical management.
Hypoxic hepatitis (HH), also known as ischemic hepatitis or shock liver, is characterized by centrilobular liver cell necrosis and sharply increasing serum aminotransferase levels in a clinical setting of cardiac, circulatory or respiratory failure. Nowadays it is recognized as the most frequent cause of acute liver injury with a reported prevalence of up to 10% in the intensive care unit. Patients with HH and vasopressor therapy have a significantly increased mortality risk in the medical intensive care unit population. ⋯ No specific therapies improving the hepatic function in patients with HH are currently established. Early recognition of HH and its underlying diseases and subsequent initiation of therapy is of central prognostic importance. The purpose of this review is to provide an update on the epidemiology, pathophysiology, and diagnostic and therapeutic options of HH.
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Wien. Klin. Wochenschr. · Jan 2009
Review Comparative Study[Mirror therapy for phantom limb pain--a systematic review].
The aim of this review was to evaluate the evidence for the treatment of phantom limb pain with mirror therapy. ⋯ More sufficiently powered randomised controlled studies with high methodological quality are mandatory to investigate the analgesic effect of mirror therapy in phantom limb pain.
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Wien. Klin. Wochenschr. · Jan 2009
Review Comparative Study[Mirror therapy for phantom limb pain--a systematic review].
The aim of this review was to evaluate the evidence for the treatment of phantom limb pain with mirror therapy. ⋯ More sufficiently powered randomised controlled studies with high methodological quality are mandatory to investigate the analgesic effect of mirror therapy in phantom limb pain.
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Wien. Klin. Wochenschr. · Jan 2009
Review Case ReportsThrombotic microangiopathy in adult-onset Still's disease: case report and review of the literature.
Coexistence of thrombotic microangiopathy and adult-onset Still's disease is extremely rare. There is increasing evidence that this association could be more than just coincidental. We report on the case of a 34-year-old male diagnosed with adult-onset Still's disease and successfully treated with intravenous glucocorticoids. ⋯ Of the four patients who were not treated with plasmapheresis, two died, one developed end-stage renal disease and one had complete remission. Awareness of the possible development of thrombotic microangiopathy in patients with adult-onset Still's disease is critical, so that treatment can be initiated early and the complications and recurrence of thrombotic microangiopathy prevented. Patients with adult-onset Still's disease should be closely monitored for signs and symptoms of thrombotic microangiopathy during the first six months after diagnosis of the Still's disease.