Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Dec 2022
At what frequency of vaccination do the vaccinated potentially pose an equal risk to the unvaccinated for transmission of SARS-CoV-2 inside restaurants in New York City?
From August 2021 to 7 March 2022, New York City prohibited indoor dining in restaurants selectively for persons who had not received a Coronavirus disease 2019 (COVID-19) vaccine. However, vaccinated persons may also be actively infected and potentially transmit severe acute respiratory syndrome coronavirus 2 (SARS-CoV‑2). Based on assuming a 7:1 ratio of COVID-19 cases in New York State for the unvaccinated versus the vaccinated, it can be estimated that when 87.5% of adults in New York City are vaccinated, the rate of unsuspected SARS-CoV‑2 infections (asymptomatic or minimally symptomatic) among vaccinated adults going to restaurants would be equivalent to that for the unvaccinated.
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Wien. Klin. Wochenschr. · Nov 2022
Meta AnalysisInflammatory bowel disease and risk of coronary heart disease : A Mendelian randomization study.
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), has been reported to be associated with an increased risk of coronary heart disease (CHD); however, the causal link between IBD and CHD is unclear. We performed Mendelian randomization (MR) analysis to investigate the association between genetically predicted IBD and CHD risk. ⋯ The results of this study suggested that genetically predicted IBD may have no causal effect on CHD risk in a population with European ancestry.
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Wien. Klin. Wochenschr. · Nov 2022
Letter ReviewRecurrent gestational diabetes : Breaking the transgenerational cycle with lifestyle modification.
This literature review is aimed at examining the benefits of lifestyle modifications in preventing recurrent gestational diabetes (GDM). Worldwide GDM affects approximately 16.2% of all pregnancies with significant maternal, fetal and neonatal complications. Almost two thirds of pregnant women with GDM will develop type 2 diabetes mellitus (T2DM) in the years following pregnancy. The proportion of women affected by GDM is on the rise and reflects increasing trends in T2DM as well as adult and childhood obesity. ⋯ This review provides an overview of the literature to date, discusses different targeted approaches and how these interventions can optimise their benefits, and where further research is required.