Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · May 2006
Comparative StudyMotor subtype and cognitive decline in Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bodies.
A previous cross sectional study found over-representation of a postural instability gait difficulty (PIGD) motor subtype in Parkinson's disease patients with dementia (PDD) and dementia with Lewy bodies (DLB), compared with Parkinson's disease (PD). ⋯ A PIGD motor subtype is associated with a faster rate of cognitive decline in PD and may be considered a risk factor for incident dementia in PD.
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J. Neurol. Neurosurg. Psychiatr. · May 2006
Time dependent validity in the diagnosis of brain death using transcranial Doppler sonography.
To evaluate the validity of transcranial Doppler (TCD) in confirming brain death from various pathological conditions. ⋯ TCD can be a confirmatory tool for diagnosing brain death. The validity of TCD diagnosed brain death depends on the time lapse between brain death and the performance of TCD. TCD of both the basilar artery and the MCAs showed significant consistency in brain death diagnosis.
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J. Neurol. Neurosurg. Psychiatr. · May 2006
Efficiency of specialist rehabilitation in reducing dependency and costs of continuing care for adults with complex acquired brain injuries.
To examine functional outcomes from a rehabilitation programme and to compare two methods for evaluating cost efficiency of rehabilitation in patients with severe complex disability. ⋯ The NPDS/NPCNA detected changes in dependency potentially associated with substantial savings in the cost of ongoing care, especially in high dependency patients. Floor effects in responsiveness of the FIM may lead to underestimation of efficiency of rehabilitation in higher dependency patients.
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J. Neurol. Neurosurg. Psychiatr. · May 2006
Orgasmic headache and middle cerebral artery dissection.
A patient with a 20 year history of primary orgasmic headache is described who, after suffering an unusually severe episode of orgasmic headache was found to have a middle cerebral artery dissection. This unusual association of primary and secondary orgasmic headache emphasises the need for a thorough diagnostic examination when the orgasmic headache differs from that of previous episodes or is associated with neurological symptoms.
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J. Neurol. Neurosurg. Psychiatr. · May 2006
Comparative StudyReduction in hypothalamic 1H-MRS metabolite ratios in patients with cluster headache.
To determine the 1H-MR spectroscopic (MRS) findings in the hypothalamus in patients with episodic cluster headache. ⋯ This study provides evidence of persistent biochemical change of the hypothalamus in patients with episodic cluster headache. Low levels of NAA/Cr and Cho/Cr suggest that cluster headache might be related to both neuronal dysfunction and changes in the membrane lipids in the hypothalamus.