Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · May 2006
Comparative StudyReduction in hypothalamic 1H-MRS metabolite ratios in patients with cluster headache.
To determine the 1H-MR spectroscopic (MRS) findings in the hypothalamus in patients with episodic cluster headache. ⋯ This study provides evidence of persistent biochemical change of the hypothalamus in patients with episodic cluster headache. Low levels of NAA/Cr and Cho/Cr suggest that cluster headache might be related to both neuronal dysfunction and changes in the membrane lipids in the hypothalamus.
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J. Neurol. Neurosurg. Psychiatr. · May 2006
Time dependent validity in the diagnosis of brain death using transcranial Doppler sonography.
To evaluate the validity of transcranial Doppler (TCD) in confirming brain death from various pathological conditions. ⋯ TCD can be a confirmatory tool for diagnosing brain death. The validity of TCD diagnosed brain death depends on the time lapse between brain death and the performance of TCD. TCD of both the basilar artery and the MCAs showed significant consistency in brain death diagnosis.
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J. Neurol. Neurosurg. Psychiatr. · May 2006
An epidemiological study of head injuries in a UK population attending an emergency department.
We aimed to identify the attendance rate for all head injuries, and for moderate to severe head injury (MSHI), in an emergency department (ED), and related risk factors for MSHI, including age, sex, area of residence, and socioeconomic status (SES). This was a retrospective descriptive epidemiological study of an ED database of head injury attendances over 6 years, carried out in an ED that serves both urban and mixed rural and urban areas, with a wide socioeconomic range, and a total population of 344,600. The main outcome measure was rates of attendance for head injury. ⋯ Head injuries are a relatively common cause of attendance at ED. There is significant variation in attendance with MSHI with regard to sex, age, socioeconomic factors, and type of area of residence. The planning and delivery of preventative and management services may be improved by such analyses.
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J. Neurol. Neurosurg. Psychiatr. · May 2006
Comparative StudyMotor subtype and cognitive decline in Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bodies.
A previous cross sectional study found over-representation of a postural instability gait difficulty (PIGD) motor subtype in Parkinson's disease patients with dementia (PDD) and dementia with Lewy bodies (DLB), compared with Parkinson's disease (PD). ⋯ A PIGD motor subtype is associated with a faster rate of cognitive decline in PD and may be considered a risk factor for incident dementia in PD.
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J. Neurol. Neurosurg. Psychiatr. · May 2006
Prevalence and intensity of pain after stroke: a population based study focusing on patients' perspectives.
To determine prevalence and intensity of pain after stroke, focusing on patients' perspectives. ⋯ Although prevalence of pain after stroke decreased with time, after 16 months 21% had moderate to severe pain. Late pain after stroke was on average more severe, and profoundly affected the patients' wellbeing.