Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Dec 2017
Review Meta AnalysisDopamine dysregulation syndrome in Parkinson's disease: a systematic review of published cases.
Dopamine dysregulation syndrome (DDS) is an uncommon complication of the treatment of Parkinson's disease, characterised by addictive behaviour and excessive use of dopaminergic medication. DDS may frequently go unrecognised or misdiagnosed. We aimed to clarify current understanding of presentation, risk factors, comorbidities and management of DDS. ⋯ Given the functional impairment, medical and psychiatric consequences and the difficulties of treatment, early identification of DDS should be a priority.