Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Jun 2018
Multicenter StudyFunctional neurological disorders in Parkinson disease.
To ascertain demographic and clinical features of Parkinson disease (PD) associated with functional neurological features. ⋯ A subtype of PD with functional neurological features is familial in one-fourth of cases and associated with more psychiatric than motor disability and greater use of diagnostic and healthcare resources than those without functional features. Functional manifestations may be prodromal to PD in one-third of patients.
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J. Neurol. Neurosurg. Psychiatr. · Jun 2018
Randomized Controlled Trial Multicenter Study Comparative StudyIntrathecal baclofen therapy versus conventional medical management for severe poststroke spasticity: results from a multicentre, randomised, controlled, open-label trial (SISTERS).
Intrathecal baclofen (ITB) is a treatment option for patients with severe poststroke spasticity (PSS) who have not reached their therapy goal with other interventions. ⋯ These data support the use of ITB therapy as an alternative to CMM for treatment of generalised PSS in adults.