European journal of clinical investigation
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Eur. J. Clin. Invest. · Jan 2022
Meta AnalysisVariants of Candidate Genes Associated with the Risk of Obstructive Sleep Apnea.
The researches on the associations between different candidate genes and obstructive sleep apnea (OSA) are inconsistent. Here, we performed a comprehensive qualitative and quantitative analysis to estimate the contribution of variants from candidate genes to the risk of OSA. ⋯ Eleven variants from the candidate genes are associated with the risk of OSA, which also show ethnicity differences in East Asian and European subgroups.
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Eur. J. Clin. Invest. · Jan 2022
Review Meta AnalysisIntravascular ultrasound insights into the unstable features of the coronary atherosclerotic plaques: a systematic review and meta-analysis.
There is a lack of a comprehensive picture of plaque geometry and composition of unstable atherosclerotic lesions as observed with intravascular ultrasound techniques. We analysed through a systematic review with meta-analysis 39 characteristics of atherosclerotic plaques in three scenarios involving culprit and non-culprit lesions from acute coronary syndromes vs stable angina pectoris patients, and culprit vs non-culprit lesions in acute coronary syndromes patients. ⋯ Culprit lesions from acute coronary patients are larger, more positively remodeled and contained more lipids as compared to stable angina lesions or non-culprit in acute patients. Non culprit lesions are also more often complicated or vulnerable in acute than stable patients.