European journal of clinical investigation
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Eur. J. Clin. Invest. · Jan 2022
Multicenter Study Observational StudyMyocardial injury in patients with SARS-CoV-2 pneumonia: pivotal role of inflammation in COVID-19.
Infection by SARS-CoV-2 may result in a systemic disease and a proportion of patients ranging 15%-44% experienced cardiac injury (CI) diagnosed by abnormal troponin levels. The aim of the present study was to analyse the clinical characteristics of a large series of hospitalized patients for COVID-19 in order to identify predisposing and/or protective factors of CI and the outcome. ⋯ This large, multicentre Italian study confirmed the high prevalence of CI and its prognostic role in hospitalized patients with COVID-19, highlighting the leading role of systemic inflammation for the occurrence of CI.