JAMA : the journal of the American Medical Association
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Randomized Controlled Trial Multicenter Study
A multifaceted intervention for quality improvement in a network of intensive care units: a cluster randomized trial.
Evidence-based practices improve intensive care unit (ICU) outcomes, but eligible patients may not receive them. Community hospitals treat most critically ill patients but may have few resources dedicated to quality improvement. ⋯ In a collaborative network of community ICUs, a multifaceted quality improvement intervention improved adoption of care practices.
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Randomized Controlled Trial Multicenter Study
Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial.
Concerns regarding the risks associated with estrogen and progesterone to manage menopausal symptoms have resulted in its declining use and increased interest in nonhormonal treatments with demonstrated efficacy for hot flashes. ⋯ Among healthy women, the use of escitalopram (10-20 mg/d) compared with placebo resulted in fewer and less severe menopausal hot flashes at 8 weeks of follow-up.
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Randomized Controlled Trial Multicenter Study Comparative Study
Radial artery grafts vs saphenous vein grafts in coronary artery bypass surgery: a randomized trial.
Arterial grafts are thought to be better conduits than saphenous vein grafts for coronary artery bypass grafting (CABG) based on experience with using the left internal mammary artery to bypass the left anterior descending coronary artery. The efficacy of the radial artery graft is less clear. ⋯ Among Veterans Affairs patients undergoing first-time elective CABG, the use of a radial artery graft compared with saphenous vein graft did not result in greater 1-year patency.
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Randomized Controlled Trial Multicenter Study Comparative Study
Behavioral therapy with or without biofeedback and pelvic floor electrical stimulation for persistent postprostatectomy incontinence: a randomized controlled trial.
Although behavioral therapy has been shown to improve postoperative recovery of continence, there have been no controlled trials of behavioral therapy for postprostatectomy incontinence persisting more than 1 year. ⋯ Among patients with postprostatectomy incontinence for at least 1 year, 8 weeks of behavioral therapy, compared with a delayed-treatment control, resulted in fewer incontinence episodes. The addition of biofeedback and pelvic floor electrical stimulation did not result in greater effectiveness.