JAMA : the journal of the American Medical Association
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Review Meta Analysis
Management of chronic prostatitis/chronic pelvic pain syndrome: a systematic review and network meta-analysis.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is common, but trial evidence is conflicting and therapeutic options are controversial. ⋯ α-Blockers, antibiotics, and combinations of these therapies appear to achieve the greatest improvement in clinical symptom scores compared with placebo. Anti-inflammatory therapies have a lesser but measurable benefit on selected outcomes. However, beneficial effects of α-blockers may be overestimated because of publication bias.