Spine
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Follow-up study. ⋯ Although in Spanish patients the influence of FAB on disability and quality of life is irrelevant, baseline FABQ score does influence LBP-related sick leave during the following year. This seems to be a direct effect of FAB, since there is no confounding by any other variable.
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This is a clinic-based cross-sectional study involving 2 health-related quality-of-life (HRQL) questionnaires. ⋯ In a spinal deformity population 8 to 18 years of age, the score distribution and reliability, internal consistency, and reproducibility of the SRS-22r were at least as good as the CHQ-CF87. The SRS-22r function, pain, and mental health domains were concurrently valid in comparison to relevant CHQ-CF87 domains, but the SRS-22r self-image and satisfaction/dissatisfaction domains were not, thereby providing health-related quality-of-life information not provided for by the CHQ-CF87.
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A genetic association study to comprehensively investigate variations of melatonin receptor 1B gene polymorphism by a set of tagging single nucleotide polymorphisms (tagSNPs) derived from the International Hapmap project. ⋯ Polymorphisms of the promoter of MTNR1B gene were associated with AIS, but not with the curve severity in AIS patients. This suggested that MTNR1B was an AIS predisposition gene.
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Case Reports
Atypical syringomyelia without cavity in a patient with Chiari malformation and hydrocephalus.
A case report is presented. ⋯ Obstruction of the cerebrospinal fluid pathways in the upper spine may result in spinal cord gray matter T2 prolongation that is reversible after restoration of patency of cerebrospinal fluid pathways and stress the importance of timely intervention to limit progression to syringomyelia.
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An updated Cochrane Review. ⋯ Surgical discectomy for carefully selected patients with sciatica due to lumbar disc prolapse provides faster relief from the acute attack than conservative management, although any positive or negative effects on the lifetime natural history of the underlying disc disease are still unclear. The evidence for other minimally invasive techniques remains unclear except for chemonucleolysis using chymopapain, which is no longer widely available.