Spine
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A descriptive study of the sacral anatomic orientation (SAO) and its association with pelvic incidence (PI). ⋯ The newly suggested parameter (SAO) may be an important tool in defining the sagittal shape of the spine and understanding its association with spinal diseases.
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A retrospective study of consecutive ankylosing spondylitis (AS) patients with spinal pseudarthrosis. ⋯ SPO at the level of pseudarthrosis was a safe and effective technique to correct sagittal imbalance without vascular complication. Surgical repair of pseudarthrosis with AIF provided successful fusion and good clinical results. For patients with lumbar hypolordosis, additional PSO was effective in restoration of sagittal balance.
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We investigated involvement of EphB/ephrinB system in neuropathic pain. ⋯ Expression of ephrinB2 is enhanced by nerve injury in neurons in DRG and spinal cord, while its receptor EphB1 is expressed in spinal cord. These results suggest that induction of ephrinB2 might activate EphB1/ephrinB2 signaling pathway to regulate synaptic plasticity and reorganization, and that ephrinB2 siRNA could be a potential therapeutic agent for neuropathic pain.
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Randomized Controlled Trial
Active exercise, education, and cognitive behavioral therapy for persistent disabling low back pain: a randomized controlled trial.
A randomized controlled trial. ⋯ This intervention program produces only modest effects in reducing LBP and disability over a 1-year period. The observation that patient preference for treatment influences outcome warrants further investigation.
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Randomized Controlled Trial
Does shaving the incision site increase the infection rate after spinal surgery?
A prospective randomized clinical study. ⋯ The shaving of the incision site immediately before spinal surgery may increase the rate of postoperative infection.